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Here are widely recognized West Coast standouts for adult cancer care. “Best” varies by cancer type and access to trials, but these centers are consistently top-ranked and NCI-designated: City of Hope (Duarte/LA area, CA) — Ranked top-5 nationwide for cancer care in U.S. News 2024-25. NCI-designated Comprehensive Cancer Center. City of Hope +1 UCSF Helen Diller Family Comprehensive Cancer Center (San Francisco, CA) — U.S. News top-10 for cancer in 2024-25; UCSF Health remains on the national Honor Roll. NCI Comprehensive. UCSF Cancer Center +2 Wikipedia +2 Stanford Cancer Institute (Palo Alto, CA) — U.S. News 2025–26 places Stanford among the top 10 cancer hospitals. NCI Comprehensive. Stanford Medicine +1 UCLA Jonsson Comprehensive Cancer Center (Los Angeles, CA) — Historically top-tier in U.S. News cancer specialty rankings; NCI Comprehensive and NCCN member. UCLA Health +1 UC San Diego Health – Moores Cancer Center (San Diego, CA) — On U.S. News national Honor Roll; only NCI Comprehensive center in San Diego. UC San Diego Health +1 Cedars-Sinai (Los Angeles, CA) — On U.S. News 2025-26 Honor Roll and top in California overall, with strong specialty rankings including cancer. Cedars-Sinai +1 Fred Hutch Cancer Center/UW Medicine (Seattle, WA) — Longtime top-ranked cancer program in the Pacific Northwest; NCI Comprehensive consortium with UW & Seattle Children’s. Fred Hutch +1 OHSU Knight Cancer Institute (Portland, OR) — Only NCI Comprehensive center in Oregon; recognized in U.S. News cancer rankings and recently bolstered by a record $2B gift. Becker's Hospital Review +2 OHSU News +2 How to choose among them Match by cancer subtype & trials. Check who leads in your specific disease and who’s running active clinical trials you could join. The NCI center finder is a good starting point. cancer.gov Logistics & coverage. Travel, support services, and insurance networks matter—most centers offer second-opinion clinics and virtual visits. (Each center’s site lists referral options; examples above.) If you tell me the cancer type/subtype, stage, and your city/insurance, I can narrow this to the best-fit clinics and active trials near you.